Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 193
interventional 134
Observational 54
Registry 5

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 94
Drug|placebo 16
Device 6
Biological 4
Procedure 3
Biological|Drug|Other 2
Combination Product 2
Biological|Drug 1
Biological|Drug|placebo 1
Biological|placebo 1
Device|Drug 1
Device|placebo 1
Drug|Other 1
Other 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 66
NA 13
China 6
Germany 6
France 4
India 3
United States|Austria|Canada|France|Germany|India|United Kingdom 3
Singapore 2
United States|Australia|Canada|United Kingdom 2
United States|Australia|United Kingdom 2
Austria|Belgium|Germany|Netherlands|United Kingdom 1
Belgium 1
Brazil 1
Czechia|Germany|Netherlands|Poland|Spain 1
Estonia 1
France|Germany|Italy|Spain|United Kingdom 1
France|United Kingdom 1
Germany|Greece|India|Israel|France|United States|Australia|Austria|Brazil|Canada|Czech Republic|Korea, Republic of|Poland|Portugal|South Africa|Spain|Switzerland|United Kingdom 1
Indonesia 1
Norway 1
Russian Federation 1
Saudi Arabia 1
Sweden 1
Syrian Arab Republic 1
United Kingdom 1
United States|Argentina|Austria|Brazil|Chile|Colombia|France|Germany|India|Israel|Italy|Japan|Peru|Poland|Spain|Turkey|United Kingdom 1
United States|Australia|Canada|Germany|Israel|New Zealand|Singapore|United Kingdom 1
United States|Australia|Canada|India|United Kingdom 1
United States|Australia|India|Mexico|Saudi Arabia 1
United States|Austria|Brazil|Canada|Czech Republic|France|Germany|Italy|United Kingdom 1
United States|Austria|France|India|Italy|Turkey 1
United States|Czechia|France|Italy|Spain|Turkey 1
United States|Germany 1
United States|Germany|Hungary|India|Israel|United Kingdom 1
United States|India 1
United States|India|Israel 1
United States|United Kingdom 1

Sites per Study

Site_count Study_Count
1 90
2 5
3 4
4 1
5 1
6 2
8 1
9 2
10 1
11 1
13 1
15 2
16 1
18 1
19 1
20 1
23 4
25 1
26 1
27 1
29 1
30 1
33 1
34 1
39 1
41 2
46 1
52 1
56 1
64 1
151 1

Phase

Phase Study_Count
Phase 3 37
Phase 2 35
N/A 19
Phase 1 13
Phase 4 13
Phase 1/Phase 2 9
Phase 2/Phase 3 7
Early Phase 1 1

Number of Arms

Number_of_Arms Count_of_Studies
1 43
2 51
3 11
4 6
8 1
NA 22

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 5 5.0000 5.00000 5.00000 5.00000 18.0000 19.0000 6
1st Qu. 5 25.0000 6.00000 10.00000 10.50000 27.0000 56.0000 13
Median 5 60.0000 12.00000 18.00000 22.00000 99.0000 146.5000 25
Mean 5 122.4211 32.69231 19.44444 40.62857 116.8571 162.6111 56
3rd Qu. 5 119.0000 17.00000 29.00000 42.50000 184.5000 224.5000 69
Max. 5 905.0000 216.00000 44.00000 315.00000 278.0000 592.0000 255

Trial Group Type

group_type Group_Count
Experimental 112
Active Comparator 59
NA 22
Placebo Comparator 21
Other 11
Sham Comparator 5
No Intervention 2

Intervention Model

intervention_model Study_Count
Parallel Assignment 70
Single Group Assignment 47
NA 12
Crossover Assignment 4
Sequential Assignment 1

Primary Purpose

primary_purpose Study_Count
Treatment 123
Diagnostic 4
Basic Science 2
NA 2
Prevention 1
Screening 1
Supportive Care 1

Observational Studies

Studies by Country

Country Study_Count
United States 22
Germany 7
France 6
United Kingdom 3
Austria 2
China 2
NA 2
Austria|Colombia|Czechia|Germany|Greece|Hungary|Ireland|Israel|Kuwait|Lebanon|Switzerland|United Arab Emirates 1
Brazil 1
Denmark 1
France|Germany|Spain|United Kingdom 1
Japan 1
Korea, Republic of 1
Poland 1
Singapore 1
United Arab Emirates 1
United States|India 1

Sites per Study

Site_count Study_Count
1 45
2 2
3 1
4 2
16 1
17 1
28 1
39 1

Enrollment Metrics

Measure Observational
Min 0.0000
1st Qu 36.0000
Median 99.0000
Mean 415.1346
3rd Qu 313.7500
Max 6300.0000

Observation Model

observational_model Study_Count
Cohort 24
NA 10
Case-Control 7
Case-Only 7
Case Control 3
Ecologic or Community 1
Family-Based 1
Other 1

Time Perspective

time_perspective Study_Count
Prospective 29
NA 9
Cross-Sectional 7
Retrospective 7
Other 2

Registries

Studies by Country

Country Study_Count
United States 2
Denmark 1
NA 1
Poland 1

Sites per Study

Site_count Study_Count
1 4
3 1

Enrollment Metrics

Measure Registries
Min 98
1st Qu 300
Median 320
Mean 2361
3rd Qu 1500
Max 9587

Registry Model

observational_model Study_Count
Cohort 3
Case-Control 1
Case-Only 1

Time Perspective

time_perspective Study_Count
Prospective 5

Follow-up

target_duration Study_Count
10 Years 3
14 Days 1
16 Weeks 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03389191 A Clinical Trial of Acyclovir for Viral Uveitis https://ClinicalTrials.gov/show/NCT03389191 Recruiting Tianjin Medical University 2019-12-31
NCT04207983 A 48 Week Study to Evaluate the Efficacy and Safety of Two (2) EYS606 Treatment Regimens in Subjects With Active Chronic Non-infectious Uveitis (CNIU) https://ClinicalTrials.gov/show/NCT04207983 Recruiting Eyevensys 2022-04-30
NCT03871361 Abatacept in Patients With Birdshot HLA A29 Uveitis https://ClinicalTrials.gov/show/NCT03871361 Recruiting Universitaire Ziekenhuizen Leuven 2020-04-01
NCT03308045 Evaluation of EYS606 in Patients With Non-infectious Posterior, Intermediate or Panuveitis https://ClinicalTrials.gov/show/NCT03308045 Recruiting Eyevensys 2020-12-31
NCT03209219 Interferon α2a Versus Cyclosporine for Refractory Behçet`s Disease Uveitis https://ClinicalTrials.gov/show/NCT03209219 Recruiting Peking Union Medical College Hospital 2020-01-31
NCT03207815 Efficacy and Safety of Filgotinib in Adults With Active Noninfectious Uveitis https://ClinicalTrials.gov/show/NCT03207815 Recruiting Gilead Sciences 2023-06-30
NCT03131154 SOLACE Trial - A Phase 3 Trial in Subjects With Non-infectious Anterior-uveitis. https://ClinicalTrials.gov/show/NCT03131154 Completed Aldeyra Therapeutics, Inc. 2019-04-19
NCT03097315 Suprachoroidal Injection of CLS-TA in Subjects Non-infectious Uveitis https://ClinicalTrials.gov/show/NCT03097315 Completed Clearside Biomedical, Inc. 2018-01-24
NCT03066869 Efficacy and Safety of H.P. ACTHAR GEL in Adults With Retinal Vasculitis https://ClinicalTrials.gov/show/NCT03066869 Recruiting Ocular Immunology and Uveitis Foundation 2020-02-29
NCT03020992 A Study to Assess the Effects of Certolizumab Pegol on the Reduction of Anterior Uveitis (AU) Flares in Axial Spondyloarthritis Subjects With a Documented History of AU https://ClinicalTrials.gov/show/NCT03020992 Completed UCB Pharma 2019-12-04
NCT02975895 Outcome of Different IOLs in Patients With and Without Uveitis https://ClinicalTrials.gov/show/NCT02975895 Active, not recruiting Vastra Gotaland Region 2020-12-31
NCT02943057 Topical 2% Ganciclovir Eye Drop for CMV Anterior Uveitis / Endotheliitis https://ClinicalTrials.gov/show/NCT02943057 Recruiting Singapore National Eye Centre 2021-12-31
NCT02931175 ACTH as A Re-emerging theRapy for Uveitis (The ACTHAR Study) https://ClinicalTrials.gov/show/NCT02931175 Recruiting Ocular Imaging Research and Reading Center 2019-07-31
NCT02843438 Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis https://ClinicalTrials.gov/show/NCT02843438 Completed University Hospital, Grenoble 2016-01-31
NCT02764697 Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients https://ClinicalTrials.gov/show/NCT02764697 Completed Tampa Bay Uveitis Center, LLC 2016-12-07
NCT02748512 Utilization and Safety of the Mk II Inserter and the Safety of the FAI Insert in Non-Infectious Uveitis https://ClinicalTrials.gov/show/NCT02748512 Completed EyePoint 2017-08-17
NCT02725177 Ocular Sarcoidosis Open Label Trial of ACTHAR Gel https://ClinicalTrials.gov/show/NCT02725177 Recruiting The Cleveland Clinic 2020-12-31
NCT02623426 Macular Edema Ranibizumab v. Intravitreal Anti-inflammatory Therapy Trial https://ClinicalTrials.gov/show/NCT02623426 Active, not recruiting JHSPH Center for Clinical Trials 2021-01-31
NCT02620618 Intravitreal Infliximab in Refractory Uveitis in Behcet’s Disease: A Safety and Efficacy Clinical Study https://ClinicalTrials.gov/show/NCT02620618 Completed Cairo University 2014-12-31
NCT02595398 Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis https://ClinicalTrials.gov/show/NCT02595398 Completed Clearside Biomedical, Inc. 2018-01-18
NCT02746991 Safety and Efficacy Study of a FAI Insert in Subjects With Chronic Non-infectious Posterior Uveitis https://ClinicalTrials.gov/show/NCT02746991 Completed EyePoint 2019-10-04
NCT03711929 LUMINA Phase III Study Assessing the Efficacy and Safety of Intravitreal Injections of 440 ug DE-109 Sirolimus for the Treatment of Active, Non-Infectious Uveitis of the Posterior Segment of the Eye https://ClinicalTrials.gov/show/NCT03711929 Recruiting Santen Inc. 2022-06-30
NCT02517619 Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution in Non-Infectious Anterior Uveitis https://ClinicalTrials.gov/show/NCT02517619 Completed Eyegate Pharmaceuticals, Inc. 2018-04-20
NCT02508337 Efficacy and Safety of XG-102 in Reduction of Post-cataract Surgery Intraocular Inflammation and Pain https://ClinicalTrials.gov/show/NCT02508337 Completed Xigen SA 2016-01-31
NCT02482129 Proof of Concept Study to Evaluate Safety and Efficacy of LME636 in the Treatment of Acute Anterior Uveitis https://ClinicalTrials.gov/show/NCT02482129 Completed Alcon Research 2016-03-21
NCT02406209 A Safety and Efficacy Study of NS2 in Patients With Anterior Uveitis https://ClinicalTrials.gov/show/NCT02406209 Completed Aldeyra Therapeutics, Inc. 2016-04-30
NCT02374060 PeriOcular and INTravitreal Corticosteroids for Uveitic Macular Edema Trial https://ClinicalTrials.gov/show/NCT02374060 Completed JHSPH Center for Clinical Trials 2017-08-30
NCT02309385 Safety and Efficacy Study of DSP-Visulex for the Treatment of Anterior Uveitis https://ClinicalTrials.gov/show/NCT02309385 Completed Aciont Inc 2017-03-03
NCT02251938 A Phase IIIb, Multinational, Multicenter, Open-Label Extension Study Assessing the Long-Term Safety of PRN Intravitreal Injections of DE-109 in Subjects With Non-Infectious Uveitis of the Posterior Segment of the Eye Who Have Participated in the SAKURA Development Program https://ClinicalTrials.gov/show/NCT02251938 Completed Santen Inc. 2017-11-01
NCT02235272 Efficacy and Safety of XG-102 in Reduction of Post-cataract Surgery Intraocular Inflammation https://ClinicalTrials.gov/show/NCT02235272 Completed Xigen SA 2015-12-31
NCT01280669 Intravitreal Sirolimus as Therapeutic Approach to Uveitis https://ClinicalTrials.gov/show/NCT01280669 Recruiting Stanford University 2021-05-31
NCT01279954 Abatacept in the Treatment of Uveitis https://ClinicalTrials.gov/show/NCT01279954 Completed Oregon Health and Science University 2017-06-30
NCT02049476 Study of the Effectiveness of Ozurdex for the Control of Uveitis https://ClinicalTrials.gov/show/NCT02049476 Completed Johns Hopkins University 2018-06-30
NCT03816397 Adalimumab in JIA-associated Uveitis Stopping Trial https://ClinicalTrials.gov/show/NCT03816397 Recruiting University of California, San Francisco 2022-12-31
NCT01939691 Macular Edema Nepafenac vs. Difluprednate Uveitis Trial https://ClinicalTrials.gov/show/NCT01939691 Recruiting University of California, San Francisco 2020-11-30
NCT01905579 Correlation Between Aqueous Protein Level and Clinical Grading of Flare and Flaremetry. https://ClinicalTrials.gov/show/NCT01905579 Completed The Eye Center and The Eye Foundation for Research in Ophthalmology 2013-07-31
NCT01900431 Phase II Study to Analyze Sarilumab in Non-Infectious Uveitis https://ClinicalTrials.gov/show/NCT01900431 Completed Sanofi 2015-07-31
NCT01870440 TAHOE: Intravitreal Dexamethasone Implant (Ozurdex) for Uveitic Macular Edema https://ClinicalTrials.gov/show/NCT01870440 Completed Northern California Retina Vitreous Associates 2015-02-28
NCT01829295 Methotrexate and Mycophenolate Mofetil for UVEITIS https://ClinicalTrials.gov/show/NCT01829295 Completed University of California, San Francisco 2018-02-21
NCT01789320 Safety Study of Suprachoroidal Triamcinolone Acetonide Via Microneedle to Treat Uveitis https://ClinicalTrials.gov/show/NCT01789320 Completed Clearside Biomedical, Inc. 2015-03-31
NCT01781936 Pilot Study of a Fluocinolone Acetonide Intravitreal Insert (FA-i) to Treat Intermediate-, Posterior-, or Panuveitis https://ClinicalTrials.gov/show/NCT01781936 Completed Duke University 2018-06-13
NCT01694186 Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal Insert https://ClinicalTrials.gov/show/NCT01694186 Completed EyePoint 2018-03-26
NCT01647529 Topical Administration of 0.15% Ganciclovir Gel for CMV Anterior Uveitis / Endotheliitis https://ClinicalTrials.gov/show/NCT01647529 Completed Singapore National Eye Centre 2013-07-31
NCT01564108 The LIMO Study, Lucentis for Treatment of Uveitic Patients With Refractory Cystoid Macular Oedema https://ClinicalTrials.gov/show/NCT01564108 Completed Moorfields Eye Hospital NHS Foundation Trust 2014-06-30
NCT01526889 Safety,Tolerability and Efficacy of Intravitreal LFG316 in Patients With Active Non-infectious Intermediate-, posterior-or Panuveitis , https://ClinicalTrials.gov/show/NCT01526889 Completed Novartis 2017-02-16
NCT01505088 Safety and Efficacy Study of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution to Treat Non-Infectious Anterior Segment Uveitis https://ClinicalTrials.gov/show/NCT01505088 Completed Eyegate Pharmaceuticals, Inc. 2013-02-28
NCT01475643 Loteprednol vs Prednisolone for the Treatment of Intraocular Inflammation Following Cataract Surgery in Children. https://ClinicalTrials.gov/show/NCT01475643 Completed Bausch & Lomb Incorporated 2017-06-02
NCT01376362 Topical Interferon Gamma for Macular Edema Secondary to Uveitis https://ClinicalTrials.gov/show/NCT01376362 Completed National Institutes of Health Clinical Center (CC) 2012-02-29
NCT01358266 Study Assessing Double-masked Uveitis Treatment https://ClinicalTrials.gov/show/NCT01358266 Completed Santen Inc. 2016-09-30
NCT04222712 A Study to Evaluate TRS01 Eye Drops in Participants With Active Non-infectious Anterior Uveitis https://ClinicalTrials.gov/show/NCT04222712 Recruiting Tarsius Pharma 2021-02-28
NCT04218565 Golimumab for the Treatment of Refractory Behcet’s Uveitis https://ClinicalTrials.gov/show/NCT04218565 Recruiting Peking Union Medical College Hospital 2022-12-15
NCT04183387 Simvastatin in Uveitis https://ClinicalTrials.gov/show/NCT04183387 Completed Federal State Budgetary Scientific Institution, Research Institute of Fundamental and Clinical Immunology 2016-01-31
NCT04162314 Beta-1,3/1,6-D-Glucan Ganoderma Lucidum on Non-infectious and Idiopathic Uveitis https://ClinicalTrials.gov/show/NCT04162314 Recruiting Fakultas Kedokteran Universitas Indonesia 2020-09-30
NCT04150770 A Clinical Trial of Infliximab for Childhood Uveitis https://ClinicalTrials.gov/show/NCT04150770 Active, not recruiting Tianjin Medical University 2020-01-31
NCT04088409 A Study of Baricitinib (LY3009104) in Participants From 2 Years to Less Than 18 Years Old With Active JIA-Associated Uveitis or Chronic Anterior Antinuclear Antibody-Positive Uveitis https://ClinicalTrials.gov/show/NCT04088409 Recruiting Eli Lilly and Company 2022-07-15
NCT04018599 Comparison of PK and Tolerability of MSB11022 Administered by AI or PFS https://ClinicalTrials.gov/show/NCT04018599 Completed Fresenius Kabi SwissBioSim GmbH 2020-03-17
NCT03847272 A Multicenter Phase 2 Single-arm Proof-of-concept Trial to Assess the Efficacy and Safety of Ustekinumab in Association With Prednisone for the Treatment of Non-infectious Severe Uveitis (NISU) https://ClinicalTrials.gov/show/NCT03847272 Recruiting Centre Hospitalier Universitaire Dijon 2022-01-31
NCT03660618 LSFG-SKIN, Laser Speckle Flowgraphy https://ClinicalTrials.gov/show/NCT03660618 Completed University of Iowa 2018-03-02
NCT03634475 A Safety Study of Intravitreal PP-001 in Patients With Chronic, Non-Infectious Uveitis https://ClinicalTrials.gov/show/NCT03634475 Active, not recruiting Panoptes Pharma GmbH 2020-11-30
NCT03606733 Suprachoroidal Injection of Triamcinolone Acetonide Using Custom Made Needle to Treat Retinal Disorders https://ClinicalTrials.gov/show/NCT03606733 Recruiting Marashi Eye Clinic 2019-08-01
NCT03598452 High-dose Intravitreal Injection of Ganciclovir for the Treatment of CMVR in HIV-negative Patients https://ClinicalTrials.gov/show/NCT03598452 Completed Aier School of Ophthalmology, Central South University 2018-01-31
NCT03586284 Systemic and Topical Antivirals for Control of Cytomegalovirus Anterior Uveitis: Treatment Outcomes https://ClinicalTrials.gov/show/NCT03586284 Recruiting University of California, San Francisco 2021-10-31
NCT03584724 Assessment of the Anti-inflammatory Effects of Norflo Oro in Acute Relapses of HLA-B27 Associated Autoimmune Uveitis https://ClinicalTrials.gov/show/NCT03584724 Active, not recruiting Eye Pharma 2021-06-30
NCT03554161 Tocilizumab for the Treatment of Refractory Behcet’s Uveitis https://ClinicalTrials.gov/show/NCT03554161 Recruiting Peking Union Medical College Hospital 2020-03-31
NCT03531853 OCT Technology Development to Assess Ocular Integrity and Characterize Ocular Integrity and Intraocular Scatterers https://ClinicalTrials.gov/show/NCT03531853 Recruiting Duke University 2020-09-30
NCT03525028 A Clinical Trial of Metformin to Decrease Glucocorticoids Side Effects in Patients With Autoimmune Uveitis https://ClinicalTrials.gov/show/NCT03525028 Recruiting Tianjin Medical University 2023-01-01
NCT01243983 Efficacy and Safety of Voclosporin to Treat Active Noninfectious Uveitis https://ClinicalTrials.gov/show/NCT01243983 Completed Lux Biosciences, Inc. 2012-12-31
NCT01232920 First-line Antimetabolites as Steroid-sparing Treatment Uveitis Pilot Trial https://ClinicalTrials.gov/show/NCT01232920 Completed University of California, San Francisco 2012-06-30
NCT01201798 Safety and Efficacy of Difluprednate 0.05% for the Treatment of Anterior Uveitis https://ClinicalTrials.gov/show/NCT01201798 Completed Alcon Research 2011-08-31
NCT01164085 Intravitreal Ketorolac for Chronic Uveitis: A Investigational Safety Study https://ClinicalTrials.gov/show/NCT01164085 Completed Vanderbilt University 2010-12-31
NCT01162070 Evaluation of a Standardized Strategy for Uveitis Etiological Diagnosis https://ClinicalTrials.gov/show/NCT01162070 Completed Hospices Civils de Lyon 2014-07-31
NCT01154010 PEMF: an Adjunct Therapy for Anterior Uveitis https://ClinicalTrials.gov/show/NCT01154010 Completed Massachusetts Eye and Ear Infirmary 2015-04-30
NCT01138657 Efficacy and Safety of Adalimumab in Patients With Active Uveitis https://ClinicalTrials.gov/show/NCT01138657 Completed AbbVie 2014-07-31
NCT01124838 Efficacy and Safety of Adalimumab in Subjects With Inactive Uveitis https://ClinicalTrials.gov/show/NCT01124838 Completed AbbVie 2015-05-31
NCT01148225 A Study of the Long-term Safety and Efficacy of Adalimumab in Subjects With Intermediate-, Posterior-, or Pan-uveitis https://ClinicalTrials.gov/show/NCT01148225 Completed AbbVie 2018-05-21
NCT01092533 Myfortic for the Treatment of Non-infectious Intermediate Uveitis https://ClinicalTrials.gov/show/NCT01092533 Completed STZ eyetrial 2015-10-31
NCT00943982 The Treatment of Uveitic Cystoid Macular Edema With Topical Interferon Gamma https://ClinicalTrials.gov/show/NCT00943982 Completed National Institutes of Health Clinical Center (CC) 2010-06-24
NCT00908466 Sirolimus as Therapeutic Approach to Uveitis https://ClinicalTrials.gov/show/NCT00908466 Completed Johns Hopkins University 2012-07-31
NCT04296838 Effects of Conbercept in Refractory Uveitic Macular Edema and VEGF https://ClinicalTrials.gov/show/NCT04296838 Recruiting Peking Union Medical College Hospital 2020-05-31
NCT00876434 Subconjunctival Sirolimus for the Treatment of Autoimmune Active Anterior Uveiti https://ClinicalTrials.gov/show/NCT00876434 Completed National Institutes of Health Clinical Center (CC) 2011-02-10
NCT00823173 Exploratory Study on Topical ESBA105 in Acute Anterior Uveitis https://ClinicalTrials.gov/show/NCT00823173 Completed ESBATech AG 2010-12-31
NCT02255032 Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis https://ClinicalTrials.gov/show/NCT02255032 Completed Clearside Biomedical, Inc. 2015-12-31
NCT01195948 Optiquel® as Corticosteroid-sparing Therapy for Chronic Noninfectious Uveitis https://ClinicalTrials.gov/show/NCT01195948 Completed National Institutes of Health Clinical Center (CC) 2013-11-30
NCT01978015 Blood-aqueous Barrier Changes After the Use of Timolol and Prostaglandin Analogues Fixed Combination in Pseudophakic Patients With POAG https://ClinicalTrials.gov/show/NCT01978015 Completed University of Campinas, Brazil 2012-07-31
NCT01385826 Effect of Adalimumab for the Treatment of Uveitis in Juvenile Idiopathic Arthritis https://ClinicalTrials.gov/show/NCT01385826 Completed Assistance Publique - Hôpitaux de Paris 2014-11-04
NCT03828019 Adalimumab vs. Conventional Immunosuppression for Uveitis Trial https://ClinicalTrials.gov/show/NCT03828019 Active, not recruiting JHSPH Center for Clinical Trials 2022-08-30
NCT00803816 Everolimus for the Treatment of Uveitis Unresponsive to Cyclosporine A https://ClinicalTrials.gov/show/NCT00803816 Completed St. Franziskus Hospital 2010-09-30
NCT03580343 Tofacitinib for Inflammatory Eye Disease https://ClinicalTrials.gov/show/NCT03580343 Active, not recruiting Washington University School of Medicine 2019-12-01
NCT02911116 Ustekinumab (STELARA) for the Treatment of Active Sight-Threatening Uveitis (STAR Study) https://ClinicalTrials.gov/show/NCT02911116 Recruiting National Institutes of Health Clinical Center (CC) 2020-12-31
NCT00790803 Pegaptanib Therapy in Non-Infectious Uveitic Cystoid Macular Edema https://ClinicalTrials.gov/show/NCT00790803 Completed Wake Forest University Health Sciences 2011-11-30
NCT00694135 Safety and Efficacy Study of Iontophoresis and Dexamethasone Phosphate to Treat Anterior Uveitis https://ClinicalTrials.gov/show/NCT00694135 Completed Eyegate Pharmaceuticals, Inc. 2009-07-31
NCT00685399 Safety and Efficacy of AIN457 in Noninfectious Uveitis https://ClinicalTrials.gov/show/NCT00685399 Completed Novartis 2013-09-30
NCT00615693 Safety, Tolerability, and Efficacy of AEB071 in the Treatment of Uveitis https://ClinicalTrials.gov/show/NCT00615693 Completed Novartis 2009-10-31
NCT00609687 Diagnostic Yield of Vitreous Biopsy in Sarcoid Uveitis https://ClinicalTrials.gov/show/NCT00609687 Completed Duke University 2007-10-31
NCT00589628 Multi Center Prospective Registry of Infliximab Use for Childhood Uveitis https://ClinicalTrials.gov/show/NCT00589628 Completed Duke University 2010-12-31
NCT00570830 Retisert and Cataract Surgery in Patients With Severe Uveitis https://ClinicalTrials.gov/show/NCT00570830 Completed Duke University 2007-11-30
NCT00570479 Prophylactic Anecortave Acetate in Patients With a Retisert Implant https://ClinicalTrials.gov/show/NCT00570479 Completed Texas Retina Associates 2010-03-31
NCT00543296 Re-implantation of a Fluocinolone Acetonide Implant for Non-infectious Uveitis Affecting the Posterior Segment https://ClinicalTrials.gov/show/NCT00543296 Completed Duke University 2007-07-31
NCT00525902 Adalimumab (Humira) in the Treatment of Refractory Non-infectious Uveitis https://ClinicalTrials.gov/show/NCT00525902 Completed Oregon Health and Science University 2010-09-30
NCT00524758 Oculusgen (Ologen) Glaucoma MMC Control in Estonia https://ClinicalTrials.gov/show/NCT00524758 Completed Pro Top & Mediking Company Limited 2011-10-31
NCT00501579 Study of Difluprednate in the Treatment of Uveitis https://ClinicalTrials.gov/show/NCT00501579 Completed Sirion Therapeutics, Inc. NA
NCT00498355 Lucentis for Inflammatory Macular Edema Trial https://ClinicalTrials.gov/show/NCT00498355 Completed University of California, San Francisco 2009-01-31
NCT00476593 Retinal OCT and (mfERG) Related to Age, Sex, and the Use of Anti-inflammatory Medications https://ClinicalTrials.gov/show/NCT00476593 Completed Norwegian University of Science and Technology 2009-12-31
NCT00468871 Safety and Efficacy of Fluocinolone Acetonide Intravitreal Implant vs Standardized Therapy https://ClinicalTrials.gov/show/NCT00468871 Completed Bausch & Lomb Incorporated 2006-06-30
NCT00405496 Study of Difluprednate Ophthalmic Emulsion in the Treatment of Uveitis https://ClinicalTrials.gov/show/NCT00405496 Completed Sirion Therapeutics, Inc. NA
NCT00444743 Phase 2 Study of MM-093 to Treat Patients With Uveitis https://ClinicalTrials.gov/show/NCT00444743 Completed Merrimack Pharmaceuticals 2008-11-30
NCT00404742 A Study of LX211 in Clinically Quiescent Non-infectious Intermediate, Anterior and Intermediate, Posterior or Pan-Uveitis https://ClinicalTrials.gov/show/NCT00404742 Completed Lux Biosciences, Inc. 2008-11-30
NCT00407082 Safety and Efficacy of Fluocinolone Acetonide Intravitreal Implants https://ClinicalTrials.gov/show/NCT00407082 Completed Bausch & Lomb Incorporated 2005-09-30
NCT00407056 Study of Difluprednate Ophthalmic Emulsion in the Treatment of Severe Uveitis https://ClinicalTrials.gov/show/NCT00407056 Completed Sirion Therapeutics, Inc. NA
NCT00406887 Study of Difluprednate Ophthalmic Emulsion in the Treatment of Uveitis https://ClinicalTrials.gov/show/NCT00406887 Completed Sirion Therapeutics, Inc. NA
NCT00404885 A Multi-center Study to Assess the Efficacy and Safety of LX211 in Active Non-infectious Anterior Uveitis https://ClinicalTrials.gov/show/NCT00404885 Completed Lux Biosciences, Inc. 2008-11-30
NCT00404612 A Study of LX211 in Active Sight Threatening, Non-infectious Intermediate-, Anterior and Intermediate-, Posterior-, or Pan-Uveitis https://ClinicalTrials.gov/show/NCT00404612 Completed Lux Biosciences, Inc. 2008-11-30
NCT00403832 Acrylate Intraocular Lenses in Cataract Surgery of Uveitis Patients https://ClinicalTrials.gov/show/NCT00403832 Completed St. Franziskus Hospital NA
NCT00344253 Randomized, Controlled Trial to Test the Efficacy of Interferon Beta in the Treatment of Intermediate Uveitis https://ClinicalTrials.gov/show/NCT00344253 Completed Heidelberg University 2011-03-31
NCT00333814 A Study of the Safety and Efficacy of a New Treatment for Non-Infectious Intermediate or Posterior Uveitis https://ClinicalTrials.gov/show/NCT00333814 Completed Allergan 2008-12-31
NCT00326508 Combination Daclizumab/Denileukin Diftitox to Treat Uveitis https://ClinicalTrials.gov/show/NCT00326508 Completed National Institutes of Health Clinical Center (CC) NA
NCT00273390 A Clinical Trial of Infliximab for Uveitis https://ClinicalTrials.gov/show/NCT00273390 Completed Oregon Health and Science University 2006-12-31
NCT00280826 Efalizumab to Treat Uveitis https://ClinicalTrials.gov/show/NCT00280826 Completed National Institutes of Health Clinical Center (CC) 2009-02-28
NCT00170729 A Study to Compare Ocular Safety and Tolerability of Eye Drops Containing Prednisolone Acetate in Patients With Intraocular Inflammation After Cataract Surgery https://ClinicalTrials.gov/show/NCT00170729 Completed Novartis 2005-02-28
NCT00167583 Interferon-alpha2a Versus Cyclosporin A for Severe Ocular Behcet`s Disease (INCYTOB) https://ClinicalTrials.gov/show/NCT00167583 Completed University Hospital Tuebingen 2014-12-31
NCT00132691 Multicenter Uveitis Steroid Treatment (MUST) Trial https://ClinicalTrials.gov/show/NCT00132691 Completed JHSPH Center for Clinical Trials 2010-12-31
NCT00130637 Human Anti-Tac (Daclizumab) to Treat Juvenile Idiopathic Arthritis (JIA)-Associated Uveitis https://ClinicalTrials.gov/show/NCT00130637 Completed National Institutes of Health Clinical Center (CC) 2008-05-31
NCT00078689 Daclizumab and Sirolimus to Treat Uveitis https://ClinicalTrials.gov/show/NCT00078689 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001311 Modified Intraocular Lens to Reduce Eye Inflammation After Cataract Surgery in Uveitis Patients https://ClinicalTrials.gov/show/NCT00001311 Completed National Institutes of Health Clinical Center (CC) NA
NCT00043667 Daclizumab Injections to Treat Non-Infectious Sight-Threatening Uveitis https://ClinicalTrials.gov/show/NCT00043667 Completed National Institutes of Health Clinical Center (CC) NA
NCT00070759 Daclizumab to Treat Non-Infectious Sight-Threatening Uveitis https://ClinicalTrials.gov/show/NCT00070759 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001614 The Safety and Efficacy of Chicken Type II Collagen on Uveitis Associated With Juvenile Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT00001614 Completed National Institutes of Health Clinical Center (CC) NA
NCT00035906 Research Study in Patients With Persistent Macular Edema https://ClinicalTrials.gov/show/NCT00035906 Completed Allergan 2004-08-31
NCT00021645 Vitamin E to Treat Uveitis-Associated Macular Edema https://ClinicalTrials.gov/show/NCT00021645 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001865 HAT in Eye Complications of Behcet’s Disease https://ClinicalTrials.gov/show/NCT00001865 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001863 Leflunomide to Treat Uveitis https://ClinicalTrials.gov/show/NCT00001863 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001862 TNRF:Fc to Treat Eye Inflammation in Juvenile Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT00001862 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001737 Cyclosporin Implant to Treat Uveitis https://ClinicalTrials.gov/show/NCT00001737 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001526 ANTI-TAC THERAPY FOR UVEITIS https://ClinicalTrials.gov/show/NCT00001526 Completed National Institutes of Health Clinical Center (CC) NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT01859299 Intestinal Bacteria and Ocular Inflammatory Disease https://ClinicalTrials.gov/show/NCT01859299 Recruiting National Institutes of Health Clinical Center (CC) 2029-12-31
NCT03899922 Monitoring Drug-induced Uveitis https://ClinicalTrials.gov/show/NCT03899922 Recruiting Groupe Hospitalier Pitie-Salpetriere 2020-04-01
NCT03339102 Post-marketing Surveillance Study of Adalimumab (Humira®) for Non-infectious Intermediate, Posterior, or Panuveitis Patients https://ClinicalTrials.gov/show/NCT03339102 Recruiting AbbVie 2020-09-30
NCT03206268 RNFL Thickness Measurements Obtained Using SD-OCT and SLP Using GDx Variable Corneal Compensation https://ClinicalTrials.gov/show/NCT03206268 Completed Hospices Civils de Lyon 2015-10-31
NCT03145025 Corneal Endothelial Cell Density in Eyes Treated With a Fluocinolone Acetonide Intravitreal Implant https://ClinicalTrials.gov/show/NCT03145025 Completed Bausch & Lomb Incorporated 2018-09-10
NCT02952001 Extension Study of Patients With Non-infectious Uveitis Who Participated in CLS1001-301 https://ClinicalTrials.gov/show/NCT02952001 Completed Clearside Biomedical, Inc. 2018-05-22
NCT02916017 HUMIRA® Long-term Treatment in Patients With Non-infectious Intermediate-, Posterior-, or Pan-uveitis https://ClinicalTrials.gov/show/NCT02916017 Active, not recruiting AbbVie 2020-09-27
NCT02765308 Aqueous Humor Dynamics and Hypertensive Uveitis https://ClinicalTrials.gov/show/NCT02765308 Completed Guy’s and St Thomas’ NHS Foundation Trust 2016-12-31
NCT02656381 Uveitis/Intraocular Inflammatory Disease Biobank (iBank) https://ClinicalTrials.gov/show/NCT02656381 Recruiting National Institutes of Health Clinical Center (CC) 2029-12-31
NCT00331331 The Vitreous Proteome and Inflammatory Mediators in Ocular Inflammatory Disease https://ClinicalTrials.gov/show/NCT00331331 Completed National Institutes of Health Clinical Center (CC) NA
NCT02466217 Phenomics in Autoimmune and Inflammatory Diseases https://ClinicalTrials.gov/show/NCT02466217 Recruiting Assistance Publique - Hôpitaux de Paris 2022-07-31
NCT01306474 Observation on the Treg in the Uveitis Patients https://ClinicalTrials.gov/show/NCT01306474 Completed Xijing Hospital 2010-08-31
NCT01299129 Functional and Morphologic Aspects of Intravitreal Triamcinolone for Uveitis-associated Cystoid Macular Edema https://ClinicalTrials.gov/show/NCT01299129 Completed Medical University of Vienna 2011-06-30
NCT02026128 Optical Coherence Tomography (OCT) in Uveitis https://ClinicalTrials.gov/show/NCT02026128 Recruiting Oregon Health and Science University 2022-12-31
NCT03971279 Dexamethasone Intravitreal Implant (Ozurdex®) for Recurrent Vogt-Koyanagi-Harada (VKH) Disease Posterior Uveitis https://ClinicalTrials.gov/show/NCT03971279 Completed Benha University 2019-11-22
NCT01539577 A Long-Term Safety Study of OZURDEX® in Clinical Practice https://ClinicalTrials.gov/show/NCT01539577 Completed Allergan 2016-03-31
NCT03889860 Objective Choroidal Thickness Measurements in Uveitis https://ClinicalTrials.gov/show/NCT03889860 Active, not recruiting Wroclaw Medical University 2025-01-01
NCT01495767 Quality of Life in Juvenile Patients With Uveitis https://ClinicalTrials.gov/show/NCT01495767 Completed Hospital Hietzing NA
NCT01384266 A Comparison of 0.5% Loteprednol Etabonate Versus 1% Prednisolone Acetate Following Cataract Surgery https://ClinicalTrials.gov/show/NCT01384266 Completed Associated Eye Care, Minnesota 2011-07-31
NCT04340505 Imaging of Uveitis Patients Receiving Injectable Fluocinolone Acetonide Implant https://ClinicalTrials.gov/show/NCT04340505 Recruiting The Cleveland Clinic 2021-08-08
NCT04200833 Golimumab in Juvenile Idiopathic Arthritis-associated Uveitis Failing Adalimumab https://ClinicalTrials.gov/show/NCT04200833 Active, not recruiting Medical University of Graz 2020-10-01
NCT04148365 Medication Compliance in the Paediatric Uveitis Population Reported by the Patients and Parents https://ClinicalTrials.gov/show/NCT04148365 Recruiting Manchester University NHS Foundation Trust 2020-07-01
NCT04101604 Biomarkers of Common Eye Diseases https://ClinicalTrials.gov/show/NCT04101604 Recruiting Sun Yat-sen University 2020-10-01
NCT03877575 Lyon Uveitis Study https://ClinicalTrials.gov/show/NCT03877575 Recruiting Hospices Civils de Lyon 2023-01-01
NCT03863782 Lyon Sarcoid Uveitis Cohort https://ClinicalTrials.gov/show/NCT03863782 Recruiting Hospices Civils de Lyon 2023-01-01
NCT03753893 Ocular Manifestations in Rheumatic Diseases https://ClinicalTrials.gov/show/NCT03753893 Active, not recruiting Lawson Health Research Institute 2020-10-01
NCT03646890 Epidemiology and Clinical Features of Uveitis in a Tertiary Referral https://ClinicalTrials.gov/show/NCT03646890 Completed University Hospital, Montpellier 2012-01-01
NCT03554824 Psychosocial Outcomes and Transition Readiness in Uveitis https://ClinicalTrials.gov/show/NCT03554824 Completed Sheffield Children’s NHS Foundation Trust 2018-08-14
NCT03472781 Demographics and Clinical Characteristics of Paediatric Intraocular Inflammation in Singapore https://ClinicalTrials.gov/show/NCT03472781 Completed Singapore National Eye Centre 2019-03-31
NCT01314469 Quality of Life in Patients With Intermediate Uveitis https://ClinicalTrials.gov/show/NCT01314469 Completed St. Franziskus Hospital NA
NCT01170481 Assessment of Retinal Nerve Fibre Layer by Optical Coherence Tomography in Uveitis Patients With Papilloedema https://ClinicalTrials.gov/show/NCT01170481 Completed St. Franziskus Hospital 2010-12-31
NCT01060787 Evaluation of Corneal Endothelial Cell Density in Subjects Who Have Had a Fluocinolone Acetonide Implant https://ClinicalTrials.gov/show/NCT01060787 Completed Bausch & Lomb Incorporated 2019-03-07
NCT00917670 Ultrastructural Changes of Trabeculectomy Specimens in Patients With Uveitic Secondary Glaucoma https://ClinicalTrials.gov/show/NCT00917670 Completed St. Franziskus Hospital 2009-09-30
NCT00874471 Uveitis Gene-Expression Profiling https://ClinicalTrials.gov/show/NCT00874471 Completed Oregon Health and Science University 2010-07-31
NCT00827086 Influencing Factors in Uveitis https://ClinicalTrials.gov/show/NCT00827086 Completed St. Franziskus Hospital NA
NCT01746537 Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography https://ClinicalTrials.gov/show/NCT01746537 Recruiting The Cleveland Clinic 2020-06-30
NCT03155243 Impact of Humira® Therapy on Ocular Inflammation, Selected Health Care Resource Utilization and Patient Reported Outcomes in Patients With Active Non-infectious Intermediate, Posterior and Panuveitis in Routine Clinical Practice https://ClinicalTrials.gov/show/NCT03155243 Completed AbbVie 2020-02-24
NCT01897935 Flare Photometry in Uveitis Patients https://ClinicalTrials.gov/show/NCT01897935 Completed ChromoLogic, LLC 2014-04-30
NCT03941184 Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity https://ClinicalTrials.gov/show/NCT03941184 Recruiting Mayo Clinic 2020-12-31
NCT00791726 Microperimetry in Macular Edema https://ClinicalTrials.gov/show/NCT00791726 Completed St. Franziskus Hospital NA
NCT00676624 Infectious Causes of Uveitis https://ClinicalTrials.gov/show/NCT00676624 Completed Statens Serum Institut 2010-09-30
NCT00647439 Genetics and Markers of Degenerative and Inflammatory Eye Diseases https://ClinicalTrials.gov/show/NCT00647439 Completed National Institutes of Health Clinical Center (CC) NA
NCT00552019 Intraocular Pressure (IOP) Assessed by Dynamic Contour Tonometer (DCT) and Goldman Applanation Tonometry (GAT) https://ClinicalTrials.gov/show/NCT00552019 Completed St. Franziskus Hospital 2009-04-30
NCT00539370 Human Samples and Data Repository https://ClinicalTrials.gov/show/NCT00539370 Completed National Institutes of Health Clinical Center (CC) NA
NCT00404482 Cyclosporine A in the Treatment of Juvenile Idiopathic Arthritis (JIA) Associated Chronic Anterior Uveitis https://ClinicalTrials.gov/show/NCT00404482 Completed St. Franziskus Hospital NA
NCT00379275 Eye and Immunogenetic Features of Sarcoidosis https://ClinicalTrials.gov/show/NCT00379275 Completed National Institutes of Health Clinical Center (CC) NA
NCT00357266 Differences in Genes and Proteins in Active and Controlled Uveitis https://ClinicalTrials.gov/show/NCT00357266 Completed National Institutes of Health Clinical Center (CC) NA
NCT00116090 Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study https://ClinicalTrials.gov/show/NCT00116090 Completed National Institutes of Health Clinical Center (CC) NA
NCT00089739 Immune Indicators of Uveitis https://ClinicalTrials.gov/show/NCT00089739 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001867 Effect of Pregnancy on Uveitis https://ClinicalTrials.gov/show/NCT00001867 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001738 Vascular Endothelial Growth Factor (VEGF) in Uveitis https://ClinicalTrials.gov/show/NCT00001738 Completed National Institutes of Health Clinical Center (CC) NA
NCT00789984 Corneal Specular Microscopy in Infectious and Noninfectious Uveitis https://ClinicalTrials.gov/show/NCT00789984 Completed Federal University of São Paulo NA
NCT00001734 Screening for NEI Clinical Studies https://ClinicalTrials.gov/show/NCT00001734 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001224 Analysis of Eye Tissue https://ClinicalTrials.gov/show/NCT00001224 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02357238 Genetics of Uveitis https://ClinicalTrials.gov/show/NCT02357238 Recruiting The Cleveland Clinic 2021-01-31
NCT03173144 Chronic Inflammatory Disease, Lifestyle and Treatment Response https://ClinicalTrials.gov/show/NCT03173144 Recruiting University of Southern Denmark 2019-03-31
NCT01837056 Prevalence of Toxoplasma Gondii and Toxocara Canis Among Patients With Uveitis https://ClinicalTrials.gov/show/NCT01837056 Completed National Institute of Health, Korea 2012-02-29
NCT01697254 The CARRA Registry https://ClinicalTrials.gov/show/NCT01697254 Completed Duke University 2015-10-31
NCT04193020 Acute and Chronic Inflammatory Disease, Lifestyle and Treatment Response https://ClinicalTrials.gov/show/NCT04193020 Recruiting Wroclaw Medical University 2025-01-01